Q)PK is a 78-year-old obese male who is diagnosed with an acute attack of gout.PMH hypertension, heart failure DH enalapril tablets 5 mg daily atenolol tablets 100 mg daily bendroflumethiazide tablets 5 mg daily aspirin ec tablets 75 mg daily He is started on colchicine tablets 500 μg twice daily for six days.
Q Gout:
A ❏ may be due to excessive production of uric acid
B ❏ may be due to increased renal elimination of uric acid
C ❏ results in the deposition of crystals of xanthine in the joints D ❏ is characterised by excessive calcium deposited in the joints E ❏ is the result of hypouricaemia
Answer:
Gout is a condition associated with either an increased production of uric acid or a decreased excretion of uric acid. Excess uric acid in the body is converted to sodium urate crystals that are deposited in joints, most commonly in the big toe. Increased levels of serum uric acid may be due to excessive production of uric acid or to excessive destruction of cells and therefore breakdown of nucleic acids, resulting in the production of uric acid.
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