Pharmacology MCQS

Q)PK is a 78-year-old obese male who is diagnosed with an acute attack of gout.PMH hypertension, heart failure DH enalapril tablets 5 mg daily atenolol tablets 100 mg daily bendroflumethiazide tablets 5 mg daily aspirin ec tablets 75 mg daily He is started on colchicine tablets 500 μg twice daily for six days.

Q Gout:
A ❏ may be due to excessive production of uric acid
B ❏ may be due to increased renal elimination of uric acid
C ❏ results in the deposition of crystals of xanthine in the joints D ❏ is characterised by excessive calcium deposited in the joints E ❏ is the result of hypouricaemia

Answer:
Gout is a condition associated with either an increased production of uric acid or a decreased excretion of uric acid. Excess uric acid in the body is converted to sodium urate crystals that are deposited in joints, most commonly in the big toe. Increased levels of serum uric acid may be due to excessive production of uric acid or to excessive destruction of cells and therefore breakdown of nucleic acids, resulting in the production of uric acid.

DrugsBank Pharmacology MCQS

Q)A  65 years Old Age Patient With A History Of Heart Disease Is Brought To The Emergency Room With Difficulty Breathing,Examination Reveals That She Has Pulmonary Edema.Which Treatment Is Indicated ?

A)Chlorthalidone
B)Furosemide
C)Hydrochlorothiazide
D)Acetazolamide
E)Spironolactone


Correct Answer : B
This is a potentially fatal situation.it is important to administor a diuretic that will reduce fluid accumulation in the lungs and thus improve oxygenation and heart function.the loop diuretic are most effective in removing large fluid volumes from the body and are the treatment of choice in this condition.in this situation furosemide should be administered intravenously .So the other choices are wrong !!

DrugsBank Pharmacology MCQs

Q)Which of The Following Drugs Can Be Used Safely In Hepatic Disease ?

A)Doxycycline
B)Chloramphenicol
C)Erythromycin
DAzithromycin
E)Streptomycin

Answer: E

DrugsBank Pharmacology MCQs

Q)The onset of action for intravenous heparin is

A)An Hour
B)Three Days
C)Immediate
D)One week

Answer :C

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DrugsBank Pharmacology MCQS

A 64 years old male experiences uncontrolled angina attacks that limits his ability to do household chores.He is adherent to a maximized dose of beta blocker with a low heart rate and a low blood pressure.He was unable to tolerate an increase in isosorbide mononitrate due to headache.Which is the most appropriate addition to his antianginal therapy ?

A)Aspirin
B)Amlodipine
C)Verapamil
D)Ronalozine

Answer :D
Ronalozine is the best answer.the patients blood pressure is low,so verapamil and amlodipine may drop blood pressure furher.Verapamil may also decrease heart rate .Ronalozine can be used when other agents are maximized,especially when blood pressure is well controlled.the patient will need a baselineECG and lab work to ensure safe use of this medication .