Q) 1.The anxiolytic action of benzodiazepines is sometimes attributed to their ability to do which of the following ?
A)Potentiate the Effects of gamma aminobutyric acid (GABA)
B)Alter the sodium ion inflow into the central nerous system.
C)interfere with the amine pump
D)Alter calcium ion flow into the central nerous system.
E)inhibit the action of monoamine oxidase.
ANSWER:A
Reason:Benzodiazepines are believed to act by potentiating the results of GABA an inhibitory amino acid within the central nervous system.Some Benzodiazepines are used for the treatment of muscle spasms and convulsive disorders.
Q) 2.Which one amongst the following medicine is indicated for the treatment of primary nocturnal enuresis?
A)Metolazone
B)Bimatoprost
C)Dicyclomine
D)Mannitol
E)Desmopressin
Answer E
Reason:Desmopressin acetate is the artificial analogue of naturally occurring human antidiuretic hormone ADH created by posterior pitiutary gland.it is administered intranasally or orally for the treatment of primary nocturnal enuresis.a single dose of the drug can turn out an antidiuretic result lasting from 8-hours.
Q) 3.Which of the following drugs are classified as macrolide?
1)Tobramycin
2)Azithromycin
3)Clarithromycin
A)1 Only
B)3 Only
C) 2 & 3 only
D)1 & 2 only
E) 1,2 & 3
Answer:C
Azithromycin and clarithromycin are each macrolide antibacterial drug agents associated with erythromycin.Tobramycin Is an aminoglycoside drug.
Q) 4.Most medication used in treating alzheimer,s disease are designed to produce that of the following effects?
A)Sympathetic
B)Dopaminergic
C)Cholinergic
D)COMT inhibition
E)Anticholinergic
Answer:C
Alzheimer,s disease is characterised by finding of brain atrophy and neuronal changes that conincide with diminshed levelsof choline acetyltranseferase.this ends up in a substantial reduction in acetylcholine production.Most medication used to treat this disease thus are aimed toward increasing the production of acetylcholine or preventing its breakdown.
Note:
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